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基因分裂和RNA剪接 - Melissa Moore P1
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本视频由科普中国和生物医学大讲堂出品

Melissa Moore (U. Mass/HHMI) Part 1: Split Genes and RNA Splicing

In the first part of her talk, Dr. Moore explains that eukaryotic pre-mRNA contains long stretches of non-protein coding sequences interspersed with protein coding regions. By recognizing specific sequences, cellular machinery splices out the non-coding introns leaving just the protein-coding exons in mRNA. Although at first glance this may seem like a wasteful process, it is splicing that facilitates the evolution of new genes, and alternative splicing that allows a limited number of genes to produce a large number of proteins.
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讲师介绍
  • 讲师:Melissa Moore(Biochemistry, Molecular Biology)

    Dr. Moore is also a professor of biochemistry and molecular pharmacology at the University of Massachusetts Medical School. She is also codirector of the UMMS RNA Therapeutics Institute (along with Victor Ambros and HHMI investigators Craig Mello and