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RNAscope®技术原理介绍
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课程介绍
RNAscope®®原位定量专利技术由美国新兴的分子病理领导者ACD公司(Advanced Cell Diagnostics, Inc., California, USA)开发,通过专利的双“Z”探针设计,使RNA原位杂交具有高度特异性、单分子检测的敏感性并有极高的信噪比,能够在单细胞水平同时定量多个RNA的表达,在获得单细胞中单拷贝RNA表达数据的同时提供完整的组织形态学信息,提高对疾病与标志物之间复杂的生物学相关性的认识,是理想的能够用于NGS和芯片技术后期转化研究技术平台。

自2011年技术推广以来,其应用已在如Nature、Science、NEJM等国际顶级期刊发表超过300篇SCI论文。研究涵盖了感染及免疫、肿瘤、神经生物学、干细胞及发育、非编码RNA、表观遗传学等基础医学领域,以及靶标鉴别和验证、临床前安全性评价和药效评估等药物开发研究。

请访问ACD官网www.acdbio.com。更多中文资料与信息请访问中国官方微信号(ACD_China)咨询。
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