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在2部分,普拉瑟介绍了她的实验室使用的设计原则设计E. coli从葡萄糖生产葡萄糖二酸。葡糖酸不在细菌中自然产生的所以,普拉瑟和她的同事们“bioprospected”从其他生物酶并在大肠杆菌中表达,构建所需的酶途径。普拉瑟走我们通过优化时序的许多步骤,酶表达的定位和水平,以产生最大的产量。
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讲师介绍
  • 讲师:Kristala Jones Prather(西奥多t.miller职业发展副教授)

    Kristala Jones Prather从马萨诸塞州所获得了加利福尼亚大学理工学院及其博士研究生学位,伯克利在化学工程。毕业后,普拉瑟加入默克研究实验室4年回国之前。普拉瑟现在是麻省理工学院化学工程系副教授与多所大学合成生物学工程的研究者她的实验室设计和构建新的合成途径在微生物转化为微小的工厂生产的小分子。普拉瑟博士已经获得了无数的奖项,为她的创新研究和卓越的教学。