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霍乱弧菌群体感应和新型抗生素 - Bonnie Bassler P2
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本视频由科普中国和生物医学大讲堂出品

Bonnie Bassler (Princeton) Part 2: Vibrio Cholerae Quorum Sensing and Novel Antibiotics

Bacteria, primitive single-celled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the basis of new therapies to be used as antibiotics. See more at http://www.ibioseminars.org
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  • 讲师:Bonnie Bassler(美国分子生物学家)

    自1994年以来任普林斯顿大学教授。 巴斯勒出生于芝加哥,并在加利福尼亚州丹维尔长大,在约翰斯·霍普金斯大学的生物化学博士学位。她做出有关细菌交流机制的关键发现,被称为群体感应。 2002年,她被授予麦克阿瑟奖。2006年当选为美国国家科学院院士。