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病毒包膜的内吞和渗透作用 - Ari Helenius P2
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本视频由科普中国和生物医学大讲堂出品

Ari Helenius (ETH Zurich) Part 2: Endocytosis and Penetration

In the second lecture, the next steps in viral infection are described. Endocytosis of plasma membrane bound viruses can occur via a number of mechanisms including caveolar, clathrin, non-clathrin, or lipid raft mediated pathways. The internalized virus is enclosed in an endosome that may undergo increasing acidification resulting in acid mediated fusion between the viral envelope and the vesicle membrane. Following membrane penetration, the virus, once again, makes use of cellular machinery such as microtubules and their motors, to transfer its genome to the nucleus. Helenius describes experiments from his lab and others that have deciphered these complex processes.
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讲师介绍
  • 讲师:Ari Helenius(Professor of Biochemistry)

    Ari Helenius has been full Professor of Biochemistry at the ETH Zurich since 1 November 1997. He is currently the head of several interdisciplinary projects in the field of protein folding and virus-cell interaction.