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基因工程与CRISPR-Cas9:一个突破性的技术诞生
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Jennifer Doudna讲述了如何学习的故事细菌战病毒感染的方式变成了基因工程技术转化了分子生物学研究。2013,Doudna和她的同事们发展了CRISPR-Cas9基因表达系统,当引入动物细胞时,使特定地点的变化,完整的基因组。CRISPR-Cas9更精确,更有效,和不太昂贵的比其他基因组编辑工具,并作为一个结果,有了广泛的研究,以前无法实现的。
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讲师介绍
  • 讲师:Jennifer Doudna(教授)

    Jennifer Doudna是部门的化学和分子教授和加利福尼亚大学的细胞生物学,伯克利,和休斯霍华德医学研究所的研究员。在她的职业生涯的早期,她研究的结构和机制的核酶(酶RNA分子)和RNA蛋白质复合物,如信号识别粒子。现在她的研究重点是理解RNA分子调控细菌基因表达的调控,通过CRISPR-Cas9系统,和真核细胞,通过RNA干扰和microRNA介导的翻译控制。为她杰出的科学贡献,她于2002年被选入美国艺术与科学学院和美国国家科学院2003,并获得生命科学2015次突破奖。