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细胞粘附、信号和癌症 - Mary Beckerle P1
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本视频由科普中国和生物医学大讲堂出品

Mary Beckerle (University of Utah) Part 1: Adhesion, Signaling and Cancer

Cell-substratum adhesion is mediated by integrins, a family of transmembrane, heterodimeric, extracellular matrix receptors that are concentrated at focal adhesions. Integin engagement influences a variety of signaling pathways and regulates cell behaviors including motility, proliferation, and survival. Disturbance of normal integrin function is associated with a variety of pathologic conditions including cancer. In the first segment of my seminar, I provide a broad overview of the cancer problem for a lay audience. Advances in our understanding of cancer as a genetic disease are discussed. The influence of cell adhesion on control of cell growth is reviewed. See more at http://www.ibiology.org
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讲师介绍
  • 讲师:Mary Beckerle(PhD)

    has served as CEO and Director of Huntsman Cancer Institute (HCI) at the University of Utah since 2006, and she was appointed in 2009 to an additional key health sciences leadership role as Associate Vice President for Cancer Affairs at the Universit