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上皮内稳态:细胞分裂
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我们的整个身体和我们的器官都覆盖着一个保护性的上皮细胞层。这些细胞不断地复制和死亡和细胞之间的平衡和分裂是维持上皮内稳态的关键。太多的细胞死亡会导致上皮细胞屏障的间隙虽然多余的分裂可能导致上皮性肿瘤的形成。Rosenblatt是理解信号调节上皮感兴趣在她说话的1部分,Rosenblatt描述了她实验室的新发现拉伸激活的上皮细胞的拉伸激活的钙离子通道(piezo1)开放,增加细胞内Ca2+水平和刺激的途径,触发细胞分裂。
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  • 讲师:Jody Rosenblatt(博士)

    Jody Rosenblatt博士获得学士学位,以优异的成绩从加利福尼亚大学,伯克利和Chiron公司,在经过一个短暂的,她搬到海湾去当一名David Morgan的技术员在加利福尼亚大学,三藩。他在加州大学博士学位期间在提姆Mitchison实验室工作。然后她搬到伦敦大学学院进行博士后培训。这是UCL,Rosenblatt发现挤压其作用在上皮内稳态。 目前,他是在一个部门的副教授肿瘤科学在犹他大学医学院和的Huntsman癌症研究所。她的实验室研究上皮细胞的细胞死亡和分裂。