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体外早期毒性测试在药物研发中的应用
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药物的毒性作用是临床前和临床阶段药物研发失败的主要因素,也是已经上市的药物退市的主要原因。传统上药物的毒性测试一般在临床前阶段完成,一旦发现药物的毒性作用而导致研发失败将造成巨大损失。在药物研发的早期进行细胞水平上的药物毒性测试将明显降低后期药物研发失败的机率从而降低研发成本。 目前, 药明康德提供一整套体外早期毒性测试,帮助我们的客户在药物研发早期发现研发化合物的毒性作用。利用包括高通量筛选,高内涵筛选,体外电生理技术等多种现代体外早提毒理服务平台,我们将高效低成本地帮助客户完成研发化合物的毒性检测及分析,这些服务将为客户的研发化合物潜在毒理风险提供一个整体认识,从而指导客户调整研发后期的体内毒理及药效学策略。
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Административный процесс должен начаться 16 октября. Судебное разбирательство может длиться годами, Рё даже быстрое урегулирование может заставить компании увеличивать СЃРєРёРґРєРё для клиентов Рё, РІ СЃРІРѕСЋ очередь, оказывать давление РЅР° РёС… рентабельность, считают инвесторы Рё аналитики. «Я думаю, что РЅР° данный момент СЏ Р±С‹ РЅРµ стал инвестировать РІ эту конкретную отрасль, Рё СЏ стараюсь соблюдать осторожность», - сказал Майкл РђСЂРѕРЅРµ, главный инвестиционный стратег State Street Global Advisors, которому принадлежат акции Генри Шейна Рё Паттерсона. Р’СЃРµ три компании опубликовали публичное заявление, отрицающее утверждения FTC. Паттерсон отказался комментировать дальше. Генри Шейн, РІ РїРёСЃСЊРјРµ, которое РѕРЅ отправил клиентам РІ четверг, сказал, что FTC «в РѕСЃРЅРѕРІРЅРѕРј РїСЂРѕСЃРёС‚ нас прекратить делать то, что РјС‹ считаем, что РјС‹ РЅРёРєРѕРіРґР° РЅРµ делали РІ первую очередь». 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