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新一代的头颈癌HPV诊断标准-RNAscope®
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课程介绍
在2012AMP年会上,来自Newcastle大学的Max Robinson介绍了美国头颈癌HPV诊断研究中使用RNAscope®技术对HPV的E6/E7转录本进行原位精准定量分析的方法,通过79例病人FFPE样本的分析,并与Qrt-PCR结果比对,证明使用RNAscope®方法获得结果可以获得非常好的诊断和预后分析。因而RNAscope®技术可以开发为HPV的临床诊断标准。

RNAscope®®原位定量专利技术由美国ACD公司(Advanced Cell Diagnostics, Inc., California, USA)开发,通过专利的双“Z”探针设计,使RNA原位杂交具有高度特异性、RNA单分子检测的敏感性并兼容自动化高通量分析,能够在单细胞水平同时定量多个RNA的表达。该视频由ACD公司制作,详细信息请访问ACD官网www.acdbio.com。更多中文资料请关注中国官方微信号(ACD_China)咨询。 文章题目:Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma. Schache AG,et al. Br J Cancer. 2013 Apr 2;108(6):1332-9.
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